Chronic obstructive pulmonary disease (COPD) is a global health problem, and since 2001,
the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy …

This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention
of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 report …

Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

Rationale: Exacerbations are key drivers of morbidity and mortality in chronic obstructive
pulmonary disease (COPD). Objectives: We compared the relative efficacy of the long-acting …

Study objectives To stratify COPD patients presenting with an acute exacerbation on the basis
of sputum color and to relate this to the isolation and viable numbers of bacteria recovered …

Exacerbations of COPD are thought to be caused by complex interactions between the host,
bacteria, viruses, and environmental pollution. These factors increase the inflammatory …

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity,
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…

PURPOSE: Viable bacteria are often isolated from airway secretions in clinically stable
patients with chronic bronchitis. We hypothesized that the number of organisms and bacterial …

Chronic obstructive pulmonary disease (COPD) is characterised by an inflammatory
response by the lungs to inhaled substances such as cigarette smoking and air pollutants. In …

AM J RESPIR CRIT CARE MED 1999;160:S49−S52.An imbalance between neutrophil proteases
and the surrounding antiproteases is critical in the normal functioning of the neutrophil. …