User profiles for Roberta De Santis Santiago

Roberta Ribeiro De Santis Santiago

Massachusetts General Hospital
Verified email at mgh.harvard.edu
Cited by 2281

[HTML][HTML] Overview: systemic inflammatory response derived from lung injury caused by SARS-CoV-2 infection explains severe outcomes in COVID-19

RB Polidoro, RS Hagan, R de Santis Santiago… - Frontiers in …, 2020 - frontiersin.org
Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial cells …

[HTML][HTML] A lung rescue team improves survival in obesity with acute respiratory distress syndrome

G Florio, M Ferrari, EA Bittner, R De Santis Santiago… - Critical Care, 2020 - Springer
Background Limited data exist regarding ventilation in patients with class III obesity [body
mass index (BMI) > 40 kg/m 2 ] and acute respiratory distress syndrome (ARDS). The aim of …

High pleural pressure prevents alveolar overdistension and hemodynamic collapse in acute respiratory distress syndrome with class III obesity. A clinical trial

R De Santis Santiago, M Teggia Droghi… - American journal of …, 2021 - atsjournals.org
Rationale: Obesity is characterized by elevated pleural pressure (Ppl) and worsening
atelectasis during mechanical ventilation in patients with acute respiratory distress syndrome (…

[HTML][HTML] Driving pressure and long-term outcomes in moderate/severe acute respiratory distress syndrome

C Toufen Junior, RR De Santis Santiago… - Annals of intensive …, 2018 - Springer
Background Acute respiratory distress syndrome (ARDS) patients may present impaired in
lung function and structure after hospital discharge that may be related to mechanical …

Bedside electrical impedance tomography unveils respiratory “chimera” in COVID-19

…, B Safaee Fakhr, RR De Santis Santiago… - American Journal of …, 2021 - atsjournals.org
In 1981, Dr. Reginald Greene and colleagues illustrated extensive pulmonary artery filling
defects in patients with different severity of acute respiratory failure by bedside angiographic …

[HTML][HTML] High pleural pressure prevents alveolar overdistension and hemodynamic collapse in acute respiratory distress syndrome with class III obesity. A clinical trial

RDS Santiago, MT Droghi, J Fumagalli… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Rationale: Obesity is characterized by elevated pleural pressure (Ppl) and worsening
atelectasis during mechanical ventilation in patients with acute respiratory distress syndrome (…

High positive end-expiratory pressure allows extubation of an obese patient

M Teggia Droghi, RR De Santis Santiago… - American journal of …, 2018 - atsjournals.org
A 59-year-old man with a body mass index of 47 kg/m2 was admitted to the ICU with septic
shock. After intubation, positive end-expiratory pressure (PEEP) was titrated to 16 cm H2O …

Monitoring of pneumothorax appearance with electrical impedance tomography during recruitment maneuvers

CCA Morais, RR De Santis Santiago… - American journal of …, 2017 - atsjournals.org
7. Oyeniran C, Sturgill JL, Hait NC, Huang WC, Avni D, Maceyka M, Newton J, Allegood JC,
Montpetit A, Conrad DH, et al. Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) …

Development of a lung rescue team to improve care of subjects with refractory acute respiratory failure

S Spina, M Capriles, RDS Santiago, G Florio… - Respiratory …, 2020 - rc.rcjournal.com
BACKGROUND: A lung-protective mechanical ventilation strategy has become the hallmark
of ventilation management for patients with acute respiratory failure. However, some …

[HTML][HTML] Quantitative dual-energy computed tomography predicts regional perfusion heterogeneity in a model of acute lung injury

…, MAM Nakamura, RDS Santiago… - Journal of computer …, 2018 - journals.lww.com
Objective The aims of this study were to investigate the ability of contrast-enhanced dual-energy
computed tomography (DECT) for assessing regional perfusion in a model of acute lung …