[HTML][HTML] Mortality comparison between the first and second/third waves among 3,795 critical COVID-19 patients with pneumonia admitted to the ICU: A multicentre …

…, J Solé-Violán, E Díaz, J Gómez, S Trefler… - The Lancet Regional …, 2021 - thelancet.com
Background It is unclear whether the changes in critical care throughout the pandemic have
improved the outcomes in coronavirus disease 2019 (COVID-19) patients admitted to the …

Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A

…, B Suberviola, R Zaragoza, S Trefler… - Journal of …, 2011 - academic.oup.com
Objectives The impact of oseltamivir on mortality in critically ill patients with 2009 pandemic
influenza A (2009 H1N1) is not clear. The main objective of this study was to investigate the …

A randomized trial of dental brushing for preventing ventilator-associated pneumonia

…, T Lisboa, A Rodriguez, R Sole, M Magret, S Trefler… - Chest, 2009 - Elsevier
Background Poor oral hygiene is associated with respiratory pathogen colonization and
secondary lung infection. The impact of adding electric toothbrushing to oral care in order to …

Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: a CHAID decision-tree analysis

…, FX Avilés-Jurado, E Díaz, P Schuetz, SI Trefler… - Journal of infection, 2016 - Elsevier
Objectives To define which variables upon ICU admission could be related to the presence
of coinfection using CHAID (Chi-squared Automatic Interaction Detection) analysis. Methods …

Negative predictive value of procalcitonin to rule out bacterial respiratory co-infection in critical covid-19 patients

…, J Solé-Violán, E Díaz, J Gómez, S Trefler… - Journal of Infection, 2022 - Elsevier
Background : Procalcitonin (PCT) and C-Reactive Protein (CRP) are useful biomarkers to
differentiate bacterial from viral or fungal infections, although the association between them …

Risk factors for noninvasive ventilation failure in critically ill subjects with confirmed influenza infection

…, M Bodí, FX Avilés-Jurado, S Trefler… - Respiratory …, 2017 - rc.rcjournal.com
BACKGROUND: Despite wide use of noninvasive ventilation (NIV) in several clinical settings,
the beneficial effects of NIV in patients with hypoxemic acute respiratory failure (ARF) due …

[HTML][HTML] Corticosteroid treatment and mortality in mechanically ventilated COVID-19-associated acute respiratory distress syndrome (ARDS) patients: a multicentre …

…, J Gómez, M Ruiz-Botella, S Trefler… - Annals of Intensive …, 2021 - Springer
Background Some unanswered questions persist regarding the effectiveness of corticosteroids
for severe coronavirus disease 2019 (COVID-19) patients. We aimed to assess the …

[HTML][HTML] Timing of intubation and ICU mortality in COVID-19 patients: a retrospective analysis of 4198 critically ill patients during the first and second waves

…, M Magret, JR Masclans, M Bodi, S Trefler… - BMC …, 2023 - Springer
Background The optimal time to intubate patients with SARS-CoV-2 pneumonia has not been
adequately determined. While the use of non-invasive respiratory support before invasive …

[HTML][HTML] Early oseltamivir treatment improves survival in critically ill patients with influenza pneumonia

…, LF Reyes, J Gómez, J Guardiola, S Trefler… - ERJ open …, 2021 - Eur Respiratory Soc
Background The relationship between early oseltamivir treatment (within 48 h of symptom
onset) and mortality in patients admitted to intensive care units (ICUs) with severe influenza is …

[HTML][HTML] Prognostic value of procalcitonin and C-reactive protein in 1608 critically ill patients with severe influenza pneumonia

…, J Gómez, M Bodí, E Díaz, E Papiol, S Trefler… - Antibiotics, 2021 - mdpi.com
Background: Procalcitonin (PCT) and C-Reactive protein (CRP) are well-established sepsis
biomarkers. The association of baseline PCT levels and mortality in pneumonia remains …