Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene, whereas chronic
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …

Coronavirus disease 2019 (COVID-19) is commonly associated with kidney damage, and the
angiotensin converting enzyme 2 (ACE2) receptor for SARS-CoV-2 is highly expressed in …

Chronic obstructive pulmonary disease (COPD), asthma and cystic fibrosis (CF) are distinct
respiratory diseases that share features such as the obstruction of small airways and disease …

The respiratory epithelium of the upper airways is a first‐line defence against inhaled irritants,
pathogens and allergens. It ensures a physical barrier provided by apical junctions and …

Background COVID-19 pandemic resulted in an unprecedented number of hospitalizations
in general wards and intensive care units (ICU). Severe and critical COVID-19 patients suffer …

With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …

In chronic obstructive pulmonary disease (COPD), epithelial changes and subepithelial
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …

Rationale: The generation of protective secretory IgA relies on the epithelial polymeric
immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive pulmonary …

In COPD, epithelial changes are prominent features in the airways, such as goblet cell
hyperplasia and squamous metaplasia. In contrast, it remains unclear whether ciliated cells are …

Progress in biotechnology has provided useful tools for tracing proteins involved in thyroid
hormone synthesis in vivo. Mono- or polyclonal antibodies are now available to detect on …