User profiles for Steven Reynolds

Steven Reynolds

Senior Clinician NIAID/NIH and Associate Professor of Medicine Johns Hopkins University
Verified email at jhmi.edu
Cited by 16511

Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial

…, MC Bacon, CFM Williams, P Opendi, SJ Reynolds… - The lancet, 2007 - thelancet.com
Background Ecological and observational studies suggest that male circumcision reduces
the risk of HIV acquisition in men. Our aim was to investigate the effect of male circumcision …

Phenotypic instability and rapid gene silencing in newly formed Arabidopsis allotetraploids

…, R Holmes-Davis, SH Reynolds, Y Stevens… - The Plant …, 2000 - academic.oup.com
Allopolyploid hybridization serves as a major pathway for plant evolution, but in its early stages
it is associated with phenotypic and genomic instabilities that are poorly understood. We …

Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis

…, NE Taylor, JG Henikoff, BJ Till, SH Reynolds… - Genetics, 2003 - academic.oup.com
Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been
possible to determine underlying rates or distributions of mutations from phenotypic screens. …

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

…, J Delabie, EB Smeland, MD Ogwang, SJ Reynolds… - Nature, 2012 - nature.com
Burkitt’s lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of
such therapy precludes its use in the elderly and in patients with endemic BL in developing …

Large-scale discovery of induced point mutations with high-throughput TILLING

BJ Till, SH Reynolds, EA Greene, CA Codomo… - Genome …, 2003 - genome.cshlp.org
TILLING (Targeting Induced LocalLesions in Genomes) is a general reverse-genetic
strategy that provides an allelic series of induced point mutations in genes of interest. High-…

Meta‐analysis of nitrogen removal in riparian buffers

PM Mayer, SK Reynolds Jr… - Journal of …, 2007 - Wiley Online Library
Riparian buffers, the vegetated region adjacent to streams and wetlands, are thought to be
effective at intercepting and reducing nitrogen loads entering water bodies. Riparian buffer …

High-throughput screening for induced point mutations

T Colbert, BJ Till, R Tompa, S Reynolds… - Plant …, 2001 - academic.oup.com
With the completion of genome sequencing projects, emphasis in genomics has shifted
from analyzing sequences to understanding gene function, and effective reverse genetic …

Efficient discovery of DNA polymorphisms in natural populations by Ecotilling

L Comai, K Young, BJ Till, SH Reynolds… - The Plant …, 2004 - Wiley Online Library
We have adapted the mutation detection technology used in Targeting Induced Local
Lesions in Genomes (TILLING) to the discovery of polymorphisms in natural populations. The …

[HTML][HTML] Male circumcision for the prevention of HSV-2 and HPV infections and syphilis

…, LH Moulton, MZ Chen, SJ Reynolds… - … England Journal of …, 2009 - Mass Medical Soc
Background Male circumcision significantly reduced the incidence of human immunodeficiency
virus (HIV) infection among men in three clinical trials. We assessed the efficacy of male …

[HTML][HTML] Discovery of induced point mutations in maize genes by TILLING

BJ Till, SH Reynolds, C Weil, N Springer, C Burtner… - BMC plant biology, 2004 - Springer
Background Going from a gene sequence to its function in the context of a whole organism
requires a strategy for targeting mutations, referred to as reverse genetics. Reverse genetics …