CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity
…, D Izawa, T Nakayama, Y Kawasaki… - The Journal of …, 2003 - journals.aai.org
CCL28 is a CC chemokine signaling via CCR10 and CCR3 that is selectively expressed in
certain mucosal tissues such as exocrine glands, trachea, and colon. Notably, these tissues …
certain mucosal tissues such as exocrine glands, trachea, and colon. Notably, these tissues …
CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells
K Hieshima, Y Kawasaki, H Hanamoto… - The Journal of …, 2004 - journals.aai.org
CCL25 (also known as thymus-expressed chemokine) and CCL28 (also known as mucosae-associated
epithelial chemokine) play important roles in mucosal immunity by recruiting IgA …
epithelial chemokine) play important roles in mucosal immunity by recruiting IgA …
Effects of expiratory rib-cage compression on oxygenation, ventilation, and airway-secretion removal in patients receiving mechanical ventilation
T Unoki, Y Kawasaki, T Mizutani, Y Fujino… - Respiratory …, 2005 - rc.rcjournal.com
… Takeshi Unoki RN PhD, Yuri Kawasaki RN, Yaeko Yanagisawa RN, Shinichi Ishimatsu MD
PhD, and Fumiko Tamura RN MSN are affiliated with the Emergency and Critical Care Center…
PhD, and Fumiko Tamura RN MSN are affiliated with the Emergency and Critical Care Center…
Identification of a High‐Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell–Based Phenotype Dissection
Y Kawasaki, H Oda, J Ito, A Niwa… - Arthritis & …, 2017 - Wiley Online Library
Objective To elucidate the genetic background of a patient with neonatal‐onset multisystem
inflammatory disease (NOMID) with no NLRP3 mutation. Methods A Japanese male child …
inflammatory disease (NOMID) with no NLRP3 mutation. Methods A Japanese male child …
Conformationally supple glucose monomers enable synthesis of the smallest cyclodextrins
…, S Wakamori, H Shimada, Y Tomabechi, Y Kawasaki… - Science, 2019 - science.org
Cyclodextrins (CDs) are cyclic oligomers of α-1,4-d-glucopyranoside and are known mainly
as hexamers to octamers. The central cavities of CDs can retain small molecules, enabling …
as hexamers to octamers. The central cavities of CDs can retain small molecules, enabling …
Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain …
The establishment of effective therapeutic interventions for prion diseases is necessary. We
report on a newly developed amyloidophilic compound that displays therapeutic efficacy …
report on a newly developed amyloidophilic compound that displays therapeutic efficacy …
Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation
…, K Kodama, E Hiejima, K Izawa, Y Kawasaki… - Journal of Experimental …, 2022 - rupress.org
Mutations in the C-terminal region of the CDC42 gene cause severe neonatal-onset
autoinflammation. Effectiveness of IL-1β–blocking therapy indicates that the pathology involves …
autoinflammation. Effectiveness of IL-1β–blocking therapy indicates that the pathology involves …
Pluripotent stem cell models of Blau syndrome reveal an IFN-γ–dependent inflammatory response in macrophages
S Takada, N Kambe, Y Kawasaki, A Niwa… - Journal of Allergy and …, 2018 - Elsevier
Background Blau syndrome, or early-onset sarcoidosis, is a juvenile-onset systemic
granulomatosis associated with a mutation in nucleotide-binding oligomerization domain 2 (NOD2). …
granulomatosis associated with a mutation in nucleotide-binding oligomerization domain 2 (NOD2). …
[HTML][HTML] Rescue of recurrent deep intronic mutation underlying cell type–dependent quantitative NEMO deficiency
…, M Bendavid, AR Gennery, Y Kawasaki… - The Journal of …, 2019 - Am Soc Clin Investig
X-linked dominant incontinentia pigmenti (IP) and X-linked recessive anhidrotic ectodermal
dysplasia with immunodeficiency (EDA-ID) are caused by loss-of-function and hypomorphic …
dysplasia with immunodeficiency (EDA-ID) are caused by loss-of-function and hypomorphic …
Anti-TNF treatment corrects IFN-γ–dependent proinflammatory signatures in blau syndrome patient–derived macrophages
Y Kitagawa, Y Kawasaki, Y Yamasaki, N Kambe… - Journal of Allergy and …, 2022 - Elsevier
Background Blau syndrome (BS) is an autoinflammatory disease associated with mutations
in nucleotide-binding oligomerization domain 2. Although treatments with anti-TNF agents …
in nucleotide-binding oligomerization domain 2. Although treatments with anti-TNF agents …