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Research ArticleSymposium Papers

Inhaled Bronchodilator Administration During Mechanical Ventilation

Alexander G Duarte
Respiratory Care June 2004, 49 (6) 623-634;
Alexander G Duarte
Division of Pulmonary and Critical Care Medicine, University of Texas Medical Branch, Galveston, Texas.
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Abstract

Inhaled bronchodilators are routinely administered to mechanically ventilated patients to relieve dyspnea and reverse bronchoconstriction. A lower percentage of the nominal dose reaches the lower respiratory tract in a mechanically ventilated patient than in a nonintubated subject, but attention to device selection, administration technique, dosing, and patient-ventilator interface can increase lower-respiratory-tract deposition in a mechanically ventilated patient. Assessing the airway response to bronchodilator by measuring airway resistance and intrinsic positive end-expiratory pressure helps guide dosing and timing of drug delivery. Selecting the optimal aerosol-generating device for a mechanically ventilated patient requires consideration of the ease, reliability, efficacy, safety, and cost of administration. With careful attention to administration technique, bronchodilator via metered-dose inhaler or nebulizer can be safe and effective with mechanically ventilated patients.

  • aerosol
  • bronchodilator
  • mechanical ventilation
  • β agonist
  • chronic obstructive pulmonary disease
  • COPD
  • asthma
  • inhalation therapy
  • noninvasive ventilation

Footnotes

  • Correspondence: Alexander G Duarte MD, Division of Pulmonary and Critical Care Medicine, University of Texas Medical Branch, Galveston TX 77555-0561. E-mail: aduarte{at}utmb.edu.
  • Copyright © 2004 by Daedalus Enterprises Inc.
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Respiratory Care: 49 (6)
Respiratory Care
Vol. 49, Issue 6
1 Jun 2004
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Inhaled Bronchodilator Administration During Mechanical Ventilation
Alexander G Duarte
Respiratory Care Jun 2004, 49 (6) 623-634;

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Inhaled Bronchodilator Administration During Mechanical Ventilation
Alexander G Duarte
Respiratory Care Jun 2004, 49 (6) 623-634;
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Keywords

  • aerosol
  • bronchodilator
  • mechanical ventilation
  • β agonist
  • chronic obstructive pulmonary disease
  • COPD
  • asthma
  • inhalation therapy
  • noninvasive ventilation

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