Monitoring Dead Space in Mechanically Ventilated Children: Volumetric Capnography Versus Time-Based Capnography

REFERENCES

1. 1.↵
   1. Hubble CL,
   2. Gentile MA,
   3. Tripp DS,
   4. Craig DM,
   5. Meliones JN,
   6. Cheifetz IM

   . Deadspace to tidal volume ratio predicts successful extubation in infants and children. Crit Care Med 2000;28(6):2034–2040.

   OpenUrlCrossRefPubMedWeb of Science
2. 2.↵
   1. Ong T,
   2. Stuart-Killion RB,
   3. Daniel BM,
   4. Presnell LB,
   5. Zhuo H,
   6. Matthay MA,
   7. Liu KD

   . Higher pulmonary dead space may predict prolonged mechanical ventilation after cardiac surgery. Pediatr Pulmonol 2009;44(5):457–463.

   OpenUrlCrossRefPubMed
3. 3.
   1. Nuckton TJ,
   2. Alonso JA,
   3. Kallet RH,
   4. Daniel BM,
   5. Pittet JF,
   6. Eisner MD,
   7. Matthay MA

   . Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002;346(17):1281–1286.

   OpenUrlCrossRefPubMedWeb of Science
4. 4.↵
   1. Kallet RH,
   2. Alonso JA,
   3. Pittet JF,
   4. Matthay MA

   . Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome. Respir Care 2004;49(9):1008–1014.

   OpenUrlAbstract/FREE Full Text
5. 5.↵
   1. Almeida-Junior AA,
   2. da Silva MT,
   3. Almeida CC,
   4. Ribeiro JD

   . Relationship between physiologic deadspace/tidal volume ratio and gas exchange in infants with acute bronchiolitis on invasive mechanical ventilation. Pediatr Crit Care Med 2007;8(4):372–377.

   OpenUrlPubMed
6. 6.
   1. Arnold JH,
   2. Bower LK,
   3. Thompson JE

   . Respiratory deadspace measurements in neonates with congenital diaphragmatic hernia. Crit Care Med 1995;23(2):371–375.

   OpenUrlCrossRefPubMedWeb of Science
7. 7.↵
   1. Ghuman AK,
   2. Newth CJ,
   3. Khemani RG

   . The association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure. Pediatr Crit Care Med 2012;13(1):11–15.

   OpenUrlPubMed
8. 8.↵
   1. Coss-Bu JA,
   2. Walding DL,
   3. David YB,
   4. Jefferson LS

   . Dead space ventilation in critically ill children with lung injury. Chest 2003;123(6):2050–2056.

   OpenUrlCrossRefPubMed
9. 9.↵
   1. Fengmei G,
   2. Jin C,
   3. Songqiao L,
   4. Congshan Y,
   5. Yi Y

   . Dead space fraction changes during PEEP titration following lung recruitment in patients with ARDS. Respir Care 2012;57(10):1578–1585.

   OpenUrlAbstract/FREE Full Text
10. 10.↵
    1. Yang Y,
    2. Huang Y,
    3. Tang R,
    4. Chen Q,
    5. Hui X,
    6. Li Y,
    7. et al

    . Optimization of positive end-expiratory pressure by volumetric capnography variables in lavage-induced acute lung injury. Respiration 2014;87(1):75–83.

    OpenUrlPubMed
11. 11.↵
    1. Kerr AA

    . Dead space ventilation in normal children and children with obstructive airways disease. Thorax 1976;31(1):63–69.

    OpenUrlAbstract/FREE Full Text
12. 12.↵
    1. Sivan Y,
    2. Eldadah MK,
    3. Cheah TE,
    4. Newth CJ

    . Estimation of arterial carbon dioxide by end-tidal and transcutaneous P_CO2 measurements in ventilated children. Pediatr Pulmonol 1992;12(3):153–157.

    OpenUrlPubMedWeb of Science
13. 13.↵
    1. Rodger MA,
    2. Jones G,
    3. Rasuli P,
    4. Raymond F,
    5. Djunaedi H,
    6. Bredeson CN,
    7. Wells PS

    . Steady-state end-tidal alveolar dead space fraction and D-dimer: bedside tests to exclude pulmonary embolism. Chest 2001;120(1):115–119.

    OpenUrlCrossRefPubMedWeb of Science
14. 14.↵
    1. Anderson CT,
    2. Breen PH

    . Carbon dioxide kinetics and capnography during critical care. Crit Care 2000;4(4):207–215.

    OpenUrlCrossRefPubMedWeb of Science
15. 15.↵
    1. Main E,
    2. Castle R,
    3. Stocks J,
    4. James I,
    5. Hatch D

    . The influence of endotracheal tube leak on the assessment of respiratory function in ventilated children. Intensive Care Med 2001;27(11):1788–1797.

    OpenUrlCrossRefPubMedWeb of Science
16. 16.↵
    1. Fowler WS

    . Lung function studies; the respiratory dead space. Am J Physiol 1948;154(3):405–416.

    OpenUrlWeb of Science
17. 17.↵
    1. Fletcher R,
    2. Jonson B,
    3. Cumming G,
    4. Brew J

    . The concept of deadspace with special reference to the single breath test for carbon dioxide. Br J Anaesth 1981;53(1):77–88.

    OpenUrlAbstract/FREE Full Text
18. 18.↵
    1. Rosenzweig EB,
    2. Starc TJ,
    3. Chen JM,
    4. Cullinane S,
    5. Timchak DM,
    6. Gersony WM,
    7. et al

    . Intravenous arginine-vasopressin in children with vasodilatory shock after cardiac surgery. Circulation 1999;100(19 Suppl):II182–II186.

    OpenUrlPubMed
19. 19.↵
    1. Bland JM,
    2. Altman DG

    . Calculating correlation coefficients with repeated observations: part 1—correlation within subjects. BMJ 1995;310(6977):446.

    OpenUrlFREE Full Text
20. 20.↵
    1. DiCiccio TJ,
    2. Efron B

    . Bootstrap confidence intervals. Stat Sci 1996;11(3):189–228.

    OpenUrlCrossRefWeb of Science
21. 21.↵
    1. Tusman G,
    2. Suarez-Sipmann F,
    3. Paez G,
    4. Alvarez J,
    5. Bohm SH

    . States of low pulmonary blood flow can be detected non-invasively at the bedside measuring alveolar dead space. J Clin Monit Comput 2012;26(3):183–190.

    OpenUrlPubMed
22. 22.↵
    1. Tusman G,
    2. Suarez-Sipmann F,
    3. Bohm SH,
    4. Borges JB,
    5. Hedenstierna G

    . Capnography reflects ventilation/perfusion distribution in a model of acute lung injury. Acta Anaesthesiol Scand 2011;55(5):597–606.

    OpenUrlCrossRefPubMedWeb of Science
23. 23.↵
    1. Proquitté H,
    2. Krause S,
    3. Rüdiger M,
    4. Wauer RR,
    5. Schmalisch G

    . Current limitations of volumetric capnography in surfactant-depleted small lungs. Pediatr Crit Care Med 2004;5(1):75–80.

    OpenUrlCrossRefPubMed
24. 24.↵
    1. Wenzel U,
    2. Wauer RR,
    3. Schmalisch G

    . Comparison of different methods for dead space measurements in ventilated newborns using CO₂-volume plot. Intensive Care Med 1999;25(7):705–713.

    OpenUrlCrossRefPubMedWeb of Science
25. 25.↵
    1. Nickles HT,
    2. Sumkauskaite M,
    3. Wang X,
    4. Wegner I,
    5. Puderbach M,
    6. Kuebler WM

    . Mechanical ventilation causes airway distension with proinflammatory sequelae in mice. Am J Physiol Lung Cell Mol Physiol 2014;307(1):L27–L37.

    OpenUrlAbstract/FREE Full Text
26. 26.↵
    1. Mok Q,
    2. Negus S,
    3. McLaren CA,
    4. Rajka T,
    5. Elliott MJ,
    6. Roebuck DJ,
    7. McHugh K

    . Computed tomography versus bronchography in the diagnosis and management of tracheobronchomalacia in ventilator dependent infants. Arch Dis Child Fetal Neonatal Ed 2005;90(4):F290–F293.

    OpenUrlAbstract/FREE Full Text
27. 27.↵
    1. Charron C,
    2. Repesse X,
    3. Bouferrache K,
    4. Bodson L,
    5. Castro S,
    6. Page B,
    7. et al

    . P_aCO2 and alveolar dead space are more relevant than P_aO2/F_IO2 ratio in monitoring the respiratory response to prone position in ARDS patients: a physiological study. Crit Care 2011;15(4):R175.

    OpenUrlPubMed
28. 28.↵
    1. Shakti D,
    2. McElhinney DB,
    3. Gauvreau K,
    4. Yarlagadda VV,
    5. Laussen PC,
    6. Betit P,
    7. et al

    . Pulmonary deadspace and postoperative outcomes in neonates undergoing stage 1 palliation operation for single ventricle heart disease. Pediatr Crit Care Med 2014;15(8):728–734.

    OpenUrlPubMed
29. 29.↵
    1. Kallet RH,
    2. Jasmer RM,
    3. Pittet JF

    . Alveolar dead-space response to activated protein C in acute respiratory distress syndrome. Respir Care 2010;55(5):617–622.

    OpenUrlAbstract/FREE Full Text
30. 30.↵
    1. Kolar M,
    2. Krizmaric M,
    3. Klemen P,
    4. Grmec S

    . Partial pressure of end-tidal carbon dioxide successful predicts cardiopulmonary resuscitation in the field: a prospective observational study. Crit Care 2008;12(5):R115.

    OpenUrlCrossRefPubMed