Mechanisms of Orthopnea in Stable Obese Subjects

References

1. 1.↵
   1. Ng M,
   2. Fleming T,
   3. Robinson M,
   4. Thomson B,
   5. Graetz N,
   6. Margono C,
   7. et al

   . Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014;384(9945):766–781.

   OpenUrlCrossRefPubMedWeb of Science
2. 2.↵
   1. Ogden CL,
   2. Carroll MD,
   3. Kit BK,
   4. Flegal KM

   . Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 2014;311(8):806–814.

   OpenUrlCrossRefPubMedWeb of Science
3. 3.↵
   1. Flegal KM,
   2. Kit BK,
   3. Orpana H,
   4. Graubard BI

   . Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 2013;309(1):71–82.

   OpenUrlCrossRefPubMedWeb of Science
4. 4.↵
   1. Beuther DA,
   2. Sutherland ER

   . Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007;175(7):661–666.

   OpenUrlCrossRefPubMedWeb of Science
5. 5.↵
   1. Peppard PE,
   2. Young T,
   3. Barnet JH,
   4. Palta M,
   5. Hagen EW,
   6. Hla KM

   . Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177(9):1006–1014.

   OpenUrlAbstract/FREE Full Text
6. 6.↵
   1. Nowbar S,
   2. Burkart KM,
   3. Gonzales R,
   4. Fedorowicz A,
   5. Gozansky WS,
   6. Gaudio JC,
   7. et al

   . Obesity-associated hypoventilation in hospitalized patients: prevalence, effects, and outcome. Am J Med 2004;116(1):1–7.

   OpenUrlCrossRefPubMedWeb of Science
7. 7.↵
   1. Jones RL,
   2. Nzekwu MM

   . The effects of body mass index on lung volumes. Chest 2006;130(3):827–833.

   OpenUrlCrossRefPubMedWeb of Science
8. 8.↵
   1. Babb TG,
   2. Ranasinghe KG,
   3. Comeau LA,
   4. Semon TL,
   5. Schwartz B

   . Dyspnea on exertion in obese women: association with an increased oxygen cost of breathing. Am J Respir Crit Care Med 2008;178(2):116–123.

   OpenUrlCrossRefPubMedWeb of Science
9. 9.↵
   1. Watson RA,
   2. Pride NB

   . Postural changes in lung volumes and respiratory resistance in subjects with obesity. J Appl Physiol 2005;98(2):512–517.

   OpenUrlAbstract/FREE Full Text
10. 10.↵
    1. Yap JC,
    2. Watson RA,
    3. Gilbey S,
    4. Pride NB

    . Effects of posture on respiratory mechanics in obesity. J Appl Physiol 1995;79(4):1199–1205.

    OpenUrlAbstract/FREE Full Text
11. 11.↵
    1. Benedik PS,
    2. Baun MM,
    3. Keus L,
    4. Jimenez C,
    5. Morice R,
    6. Bidani A,
    7. Meininger JC

    . Effects of body position on resting lung volume in overweight and mildly to moderately obese subjects. Respir Care 2009;54(3):334–339.

    OpenUrlAbstract/FREE Full Text
12. 12.↵
    1. Ferretti A,
    2. Giampiccolo P,
    3. Cavalli A,
    4. Milic-Emili J,
    5. Tantucci C

    . Expiratory flow limitation and orthopnea in massively obese subjects. Chest 2001;119(5):1401–1408.

    OpenUrlCrossRefPubMedWeb of Science
13. 13.↵
    1. Eltayara L,
    2. Becklake MR,
    3. Volta CA,
    4. Milic-Emili J

    . Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1996;154(6 Pt 1):1726–1734.

    OpenUrlCrossRefPubMedWeb of Science
14. 14.↵
    1. Borg GA

    . Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982;14(5):377–381.

    OpenUrlPubMedWeb of Science
15. 15.↵
    1. Wanger J,
    2. Clausen JL,
    3. Coates A,
    4. Pedersen OF,
    5. Brusasco V,
    6. Burgos F,
    7. et al

    . Standardisation of the measurement of lung volumes. Eur Respir J 2005;26(3):511–522.

    OpenUrlAbstract/FREE Full Text
16. 16.↵
    1. Koulouris NG,
    2. Valta P,
    3. Lavoie A,
    4. Corbeil C,
    5. Chassé M,
    6. Braidy J,
    7. Milic-Emili J

    . A simple method to detect expiratory flow limitation during spontaneous breathing. Eur Respir J 1995;8(2):306–313.

    OpenUrlAbstract
17. 17.↵
    1. McCarthy DS,
    2. Spencer R,
    3. Greene R,
    4. Milic-Emili J

    . Measurement of “closing volume” as a simple and sensitive test for early detection of small airway disease. Am J Med 1972;52(6):747–753.

    OpenUrlCrossRefPubMed
18. 18.↵
    1. Pellegrino R,
    2. Viegi G,
    3. Brusasco V,
    4. Crapo RO,
    5. Burgos F,
    6. Casaburi R,
    7. et al

    . Interpretative strategies for lung function tests. Eur Respir J 2005;26(5):948–968.

    OpenUrlFREE Full Text
19. 19.↵
    1. Shrout PE,
    2. Fleiss JL

    . Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979;86(2):420–428.

    OpenUrlCrossRefPubMedWeb of Science
20. 20.↵
    1. Gerlach Y,
    2. Wiliams MT,
    3. Coates AM

    . Weighing up the evidence: a systematic review of measures used for the sensation of breathlessness in obesity. Int J Obes 2013;37(3):341–349.

    OpenUrl
21. 21.↵
    1. Cazzola M,
    2. MacNee W,
    3. Martinez FJ,
    4. Rabe KF,
    5. Franciosi LG,
    6. Barnes PJ,
    7. et al

    . Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J 2008;31(2):416–469.

    OpenUrlAbstract/FREE Full Text
22. 22.↵
    1. Gennimata SA,
    2. Palamidas A,
    3. Karakontaki F,
    4. Kosmas EN,
    5. Koutsoukou A,
    6. Loukides S,
    7. et al

    . Pathophysiology of evolution of small airways disease to overt COPD. COPD 2010;7(4):269–275.

    OpenUrl
23. 23.↵
    1. Milic-Emili J,
    2. Torchio R,
    3. D'Angelo E

    . Closing volume: a reappraisal (1967-2007). Eur J Appl Physiol 2007;99(6):567–583.

    OpenUrlCrossRefPubMedWeb of Science
24. 24.↵
    1. Tantucci C,
    2. Duguet A,
    3. Ferretti A,
    4. Mehiri S,
    5. Arnulf I,
    6. Zelter M,
    7. et al

    . Effect of negative expiratory pressure on respiratory system flow resistance in awake snorers and nonsnorers. J Appl Physiol 1999;87(3):969–976.

    OpenUrlAbstract/FREE Full Text
25. 25.↵
    1. Insalaco G,
    2. Romano S,
    3. Marrone O,
    4. Salvaggio A,
    5. Bonsignore G

    . A new method of negative expiratory pressure test analysis detecting upper airway flow limitation to reveal obstructive sleep apnea. Chest 2005;128(4):2159–2165.

    OpenUrlCrossRefPubMed
26. 26.↵
    1. Baydur A,
    2. Wilkinson L,
    3. Mehdian R,
    4. Bains B,
    5. Milic-Emili J

    . Extrathoracic expiratory flow limitation in obesity and obstructive and restrictive disorders: effects of increasing negative expiratory pressure. Chest 2004;125(1):98–105.

    OpenUrlCrossRefPubMedWeb of Science