Inhaled Nitric Oxide: In Vitro Analysis of Continuous Flow Noninvasive Delivery via Nasal Cannula

References

1. 1.↵
   1. Frostell C,
   2. Fratacci M,
   3. Wain J,
   4. Jones R,
   5. Zapol W

   . Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 1991;83(6):2038-2047.

   OpenUrlAbstract/FREE Full Text
2. 2.↵
   American Academy of Pediatrics. Committee on Fetus and Newborn. Use of inhaled nitric oxide. Pediatrics 2000;106(2):344-345.

   OpenUrlAbstract/FREE Full Text
3. 3.
   1. Checchia P,
   2. Bronicki R,
   3. Goldstein B

   . Review of inhaled nitric oxide in the pediatric cardiac surgery setting. Pediatr Cardiol 2012;33(4):493-505.

   OpenUrlCrossRefPubMed
4. 4.↵
   1. Oz MC,
   2. Ardehali A

   . Collective review: perioperative uses of inhaled nitric oxide in adults. Heart Surg Forum 2004;7(6):E584-E589.

   OpenUrlPubMedWeb of Science
5. 5.↵
   1. Creagh-Brown BC,
   2. Griffiths MJ,
   3. Evans TW

   . Bench-to-bedside review: inhaled nitric oxide therapy in adults. Crit Care 2009;13(3):221.

   OpenUrlPubMed
6. 6.↵
   1. Griffiths MJD,
   2. Evans TW

   . Inhaled nitric oxide therapy in adults. N Engl J Med 2005;353(25):2683-2695.

   OpenUrlCrossRefPubMedWeb of Science
7. 7.↵
   1. Martin AR,
   2. Jackson C,
   3. Fromont S,
   4. Pont C,
   5. Katz IM,
   6. Caillobotte G

   . An injection and mixing element for delivery and monitoring of inhaled nitric oxide. Biomed Eng Online 2016;15(1):103.

   OpenUrl
8. 8.
   1. Bhatraju P,
   2. Crawford J,
   3. Hall M,
   4. Lang JD

   . Inhaled nitric oxide: current clinical concepts. Nitric Oxide 2015;50:114-128.

   OpenUrlCrossRefPubMed
9. 9.↵
   1. Tremblay J,
   2. Couture ÉJ,
   3. Albert M,
   4. Beaubien-Souligny W,
   5. Elmi-Sarabi M,
   6. Lamarche Y,
   7. et al

   . Noninvasive administration of inhaled nitric oxide and its hemodynamic effects in patients with acute right ventricular dysfunction. J. Cardiothorac. Vasc. Anesth 2019;33(3):642-647.

   OpenUrl
10. 10.↵
    1. Westfelt UN,
    2. Lundin S,
    3. Stenqvist O

    . Uptake of inhaled nitric oxide in acute lung injury. Acta Anaesthesiol Scand 1997;41(7):818-823.

    OpenUrlPubMedWeb of Science
11. 11.
    1. Imanaka H,
    2. Hess D,
    3. Kirmse M,
    4. Bigatello LM,
    5. Kacmarek RM,
    6. Steudel W,
    7. Hurford WE

    . Inaccuracies of nitric oxide delivery systems during adult mechanical ventilation. Anesthesiology 1997;86(3):676-688.

    OpenUrlCrossRefPubMedWeb of Science
12. 12.↵
    1. Young JD,
    2. Roberts M,
    3. Gale LB

    . Laboratory evaluation of the I-NOvent nitric oxide delivery device. Br J Anaesth 1997;79(3):398-401.

    OpenUrlCrossRefPubMed
13. 13.↵
    1. Tworetzky W,
    2. Bristow J,
    3. Moore P,
    4. Brook MM,
    5. Segal MR,
    6. Brasch RC,
    7. et al

    . Inhaled nitric oxide in neonates with persistent pulmonary hypertension. Lancet 2001;357(9250):118-120.

    OpenUrlCrossRefPubMedWeb of Science
14. 14.↵
    1. Humbert M,
    2. Evgenov OV,
    3. Stasch J

    1. Abman SH

    . Inhaled nitric oxide for the treatment of pulmonary arterial hypertension. In: Humbert M, Evgenov OV, Stasch J, editors. Pharmacotherapy of pulmonary hypertension: handbook of experimental pharmacology, vol 218. Berlin: Springer-Verlag; 2013; 257-276.

    OpenUrl
15. 15.↵
    1. Barst RJ,
    2. Channick R,
    3. Dunbar I,
    4. Goldstein B

    . Clinical perspectives with long-term pulsed inhaled nitric oxide for the treatment of pulmonary arterial hypertension. Pulm Circ 2012;2(2):139-147.

    OpenUrlCrossRefPubMed
16. 16.↵
    1. Quinn D

    , on behalf of Bellerophon Pulse Technologies. Clinical study of pulsed, inhaled nitric oxide versus placebo in symptomatic subjects with PAH (INOvation-1). Aug 6, 2019. Available at: https://clinicaltrials.gov/ct2/show/study/NCT02725372. Accessed September 5, 2019.
17. 17.↵
    1. Tiep B,
    2. Carter R

    . Oxygen conserving devices and methodologies. Chron Respir Dis 2008;5(2):109-114.

    OpenUrlCrossRefPubMed
18. 18.↵
    1. Martin AR,
    2. Jackson C,
    3. Katz IM,
    4. Caillibotte G

    . Variability in uptake efficiency for pulsed versus constant concentration delivery of inhaled nitric oxide. Med Gas Res 2014;4(1):1.

    OpenUrl
19. 19.↵
    1. Hajian B,
    2. De Backer J,
    3. Vos W,
    4. Van Holsbeke C,
    5. Ferreira F,
    6. Quinn DA,
    7. et al

    . Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension. Int J Chron Obstruct Pulmon Dis 2016;11:1533-1541.

    OpenUrl
20. 20.↵
    1. Yaacoby-Bianu K,
    2. Gur M,
    3. Toukan Y,
    4. Nir V,
    5. Hakim F,
    6. Geffen Y,
    7. et al

    . Compassionate nitric oxide adjuvant treatment of persistent mycobacterium infection in cystic fibrosis patients. Pediatr Infect Dis J 2018;37(4):336-338.

    OpenUrl
21. 21.↵
    1. Berra L,
    2. Lei C,
    3. Su B,
    4. Dong H,
    5. Fakhr BS,
    6. Grassi LG,
    7. et al

    . Protocol for a randomized controlled trial testing inhaled nitric oxide therapy in spontaneously breathing patients with COVID-19. medRxiv 2020 [Epub ahead of print].
22. 22.↵
    1. Chen JZ,
    2. Katz IM,
    3. Pichelin M,
    4. Zhu K,
    5. Caillibotte G,
    6. Noga ML,
    7. et al

    . Comparison of pulsed versus continuous oxygen delivery using realistic adult nasal airway replicas. Int J Chron Obstruct Pulmon Dis 2017;12:2559-2571.

    OpenUrl
23. 23.↵
    1. Chen JZ,
    2. Katz IM,
    3. Pichelin M,
    4. Zhu K,
    5. Caillibotte G,
    6. Finlay WH,
    7. et al

    . In vitro-in silico comparison of pulsed oxygen delivery from portable oxygen concentrators versus continuous flow oxygen delivery. Respir Care 2019;64(2):117-129.

    OpenUrlAbstract/FREE Full Text
24. 24.↵
    1. Katz I,
    2. Chen J,
    3. Duong K,
    4. Zhu K,
    5. Pichelin M,
    6. Caillibotte G,
    7. et al

    . Dose variability of supplemental oxygen therapy with open patient interfaces based on in vitro measurements using a physiologically realistic upper airway model. Respir Res 2019;20(1):149.

    OpenUrl
25. 25.↵
    1. Duprez F,
    2. Mashayekhi S,
    3. Cuvelier G,
    4. Legrand A,
    5. Reychler G

    . A new formula for predicting the fraction of delivered oxygen during low-flow oxygen therapy. Respir Care 2018;63(12):1528-1534.

    OpenUrlAbstract/FREE Full Text
26. 26.↵
    1. Golshahi L,
    2. Noga ML,
    3. Thompson RB,
    4. Finlay WH

    . In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing. J Aerosol Sci 2011;42(7):474-488.

    OpenUrl
27. 27.↵
    US Food and Drug Administration. Guidance document for premarket notification submissions for nitric oxide delivery apparatus, nitric oxide analyzer and nitrogen dioxide analyzer. 2000. Available at: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-document-premarket-notification-submissions-nitric-oxide-delivery-apparatus-nitric-oxide. Accessed August 4, 2020.
28. 28.↵
    1. Finlay WH

    . The mechanics of inhaled pharmaceutical aerosols: an introduction. San Diego: Academic Press; 2001.
29. 29.↵
    1. Chatila W,
    2. Nugent T,
    3. Vance G,
    4. Gaughan J,
    5. Criner GJ

    . The effects of high-flow vs low-flow oxygen on exercise in advanced obstructive airways disease. Chest 2004;126(4):1108-1115.

    OpenUrlCrossRefPubMed
30. 30.↵
    1. Hudgel DW,
    2. Martin RJ,
    3. Capehart M,
    4. Johnson B,
    5. Hill P

    . Contribution of hypoventilation to sleep oxygen desaturation in chronic obstructive pulmonary disease. J Appl Physiol Respir Environ Exerc Physiol 1983;55(3):669-677.

    OpenUrlPubMedWeb of Science
31. 31.↵
    1. Langer AW,
    2. Hutcheson JS,
    3. Charlton JD,
    4. McCubbin JA,
    5. Obrist PA,
    6. Stoney CM

    . On-line minicomputerized measurement of cardiopulmonary function on a breath-by-breath basis. Psychophysiology 1985;22(1):50-58.

    OpenUrlPubMed
32. 32.↵
    1. Taylor JR

    . An introduction to error analysis: the study of uncertainties in physical measurements. Sausalito, CA: University Science Books; 1997:327.
33. 33.↵
    1. Ghadimi K,
    2. Rajagopal S

    . Nasally inhaled nitric oxide for sudden right-sided heart failure in the intensive care unit: no time like the present. J Cardiothorac Vasc Anesth 2019;33(3):648-650.

    OpenUrl
34. 34.↵
    1. DiBlasi RM,
    2. Dupras D,
    3. Kearney C,
    4. Costa E Jr.,
    5. Griebel JL

    . Nitric oxide delivery by neonatal noninvasive respiratory support devices. Respir Care 2015;60(2):219-230.

    OpenUrlAbstract/FREE Full Text
35. 35.↵
    1. Tsukahara H,
    2. Ishida T,
    3. Mayumi M

    . Gas-phase oxidation of nitric oxide: chemical kinetics and rate constant. Nitric Oxide 1999;3(3):191-198.

    OpenUrlCrossRefPubMedWeb of Science
36. 36.↵
    1. Tavernini S,
    2. Church TK,
    3. Lewis DA,
    4. Martin AR,
    5. Finlay WH

    . Scaling an idealized infant nasal airway geometry to mimic inertial filtration of neonatal nasal airways. J Aerosol Sci 2018;118:14-21.

    OpenUrl
37. 37.↵
    1. O'Reilly Nugent A,
    2. Kelly PT,
    3. Stanton J,
    4. Swanney MP,
    5. Graham B,
    6. Beckert L

    . Measurement of oxygen concentration delivered via nasal cannulae by tracheal sampling. Respirology 2014;19(4):538-543.

    OpenUrlCrossRefPubMed