Identifying Subjects at Risk for Diaphragm Atrophy During Mechanical Ventilation Using Routinely Available Clinical Data

Martin Urner; Nicholas Mitsakakis; Stefannie Vorona; Lu Chen; Michael C Sklar; Martin Dres; Gordon D Rubenfeld; Laurent J Brochard; Niall D Ferguson; Eddy Fan; Ewan C Goligher

doi:10.4187/respcare.08223

Research ArticleOriginal Research

Identifying Subjects at Risk for Diaphragm Atrophy During Mechanical Ventilation Using Routinely Available Clinical Data

Martin Urner, Nicholas Mitsakakis, Stefannie Vorona, Lu Chen, Michael C Sklar, Martin Dres, Gordon D Rubenfeld, Laurent J Brochard, Niall D Ferguson, Eddy Fan and Ewan C Goligher

Respiratory Care April 2021, 66 (4) 551-558; DOI: https://doi.org/10.4187/respcare.08223

Martin Urner

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

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Nicholas Mitsakakis

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

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Stefannie Vorona

Department of Medicine, Division of Respirology, University Health Network, Toronto, Canada.

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Lu Chen

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada.

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Michael C Sklar

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

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Martin Dres

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada.

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Gordon D Rubenfeld

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Program in Trauma, Emergency, and Critical Care Organization, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada.

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Laurent J Brochard

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada.

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Niall D Ferguson

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Department of Medicine, Division of Respirology, University Health Network, Toronto, Canada.

Departments of Medicine and Physiology, University of Toronto, Toronto, Canada.

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Eddy Fan

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Department of Medicine, Division of Respirology, University Health Network, Toronto, Canada.

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Ewan C Goligher

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

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For correspondence: ewan.goligher@mail.utoronto.ca

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Identifying Subjects at Risk for Diaphragm Atrophy During Mechanical Ventilation Using Routinely Available Clinical Data

Martin Urner, Nicholas Mitsakakis, Stefannie Vorona, Lu Chen, Michael C Sklar, Martin Dres, Gordon D Rubenfeld, Laurent J Brochard, Niall D Ferguson, Eddy Fan, Ewan C Goligher

Respiratory Care Apr 2021, 66 (4) 551-558; DOI: 10.4187/respcare.08223

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Identifying Subjects at Risk for Diaphragm Atrophy During Mechanical Ventilation Using Routinely Available Clinical Data

Martin Urner, Nicholas Mitsakakis, Stefannie Vorona, Lu Chen, Michael C Sklar, Martin Dres, Gordon D Rubenfeld, Laurent J Brochard, Niall D Ferguson, Eddy Fan, Ewan C Goligher

Respiratory Care Apr 2021, 66 (4) 551-558; DOI: 10.4187/respcare.08223

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diaphragm thickening
diaphragm thickening fraction
machine learning
random forest
spontaneous breathing
diaphragm atrophy

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