Abstract
OBJECTIVE: To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients.
METHODS: Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period.
RESULTS: In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P = .004).
CONCLUSIONS: The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.
Footnotes
- Correspondence: Gerald C Smaldone MD PhD, Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook, HSC T 17-040, Stony Brook NY 11794. E-mail: gsmaldone{at}notes.cc.sunysb.edu.
Dr Smaldone has disclosed a relationship with Pari Respiratory Equipment. The other authors have disclosed no conflicts of interest.
- Copyright © 2009 by Daedalus Enterprises Inc.
