High-Dose Nitric Oxide From Pressurized Cylinders and Nitric Oxide Produced by an Electric Generator From Air

References

1. 1.↵
   1. Barrington KJ,
   2. Finer N,
   3. Pennaforte T,
   4. Altit G

   . Nitric oxide for respiratory failure in infants born at or near term. Cochrane Database Syst Rev 2017;CD000399. Available at: http://doi.wiley.com/10.1002/14651858.CD000399.pub3.
2. 2.↵
   1. Clark RH,
   2. Kueser TJ,
   3. Walker MW,
   4. Southgate WM,
   5. Huckaby JL,
   6. Perez JA,
   7. et al

   . Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. N Engl J Med 2000;342(7):469-474.

   OpenUrlCrossRefPubMedWeb of Science
3. 3.↵
   1. Troncy E,
   2. Collet JP,
   3. Shapiro S,
   4. Guimond JG,
   5. Blair L,
   6. Ducruet T,
   7. et al

   . Inhaled nitric oxide in acute respiratory distress syndrome: a pilot randomized controlled study. Am J Respir Crit Care Med 1998;157(5 Pt 1):1483-1488.

   OpenUrlCrossRefPubMedWeb of Science
4. 4.
   1. Gerlach H,
   2. Keh D,
   3. Semmerow A,
   4. Busch T,
   5. Lewandowski K,
   6. Pappert DM,
   7. et al

   . Dose–response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective randomized controlled study. Am J Respir Crit Care Med 2003;167(7):1008-1015.

   OpenUrlCrossRefPubMedWeb of Science
5. 5.↵
   1. Taylor RW,
   2. Zimmerman JL,
   3. Dellinger RP,
   4. Straube RC,
   5. Criner GJ,
   6. Kenneth DJ,
   7. et al

   . Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA 2004;291(13):1603-1609.

   OpenUrlCrossRefPubMedWeb of Science
6. 6.↵
   1. Wiegand SB,
   2. Traeger L,
   3. Nguyen HK,
   4. Rouillard KR,
   5. Fischbach A,
   6. Zadek F,
   7. et al

   . Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia. Redox Biol 2021;39:101826.

   OpenUrl
7. 7.↵
   1. Hedenstierna G,
   2. Chen L,
   3. Hedenstierna M,
   4. Lieberman R,
   5. Fine DH

   . Nitric oxide dosed in short bursts at high concentrations may protect against COVID-19. Nitric Oxide 2020;103:1-3.

   OpenUrl
8. 8.↵
   1. Tal A,
   2. Greenberg D,
   3. Av-Gay Y,
   4. Golan-Tripto I,
   5. Feinstein Y,
   6. Ben-Shimol S,
   7. et al

   . Nitric oxide inhalations in bronchiolitis: a pilot randomized double-blinded controlled trial. Pediatr Pulmonol 2018;53(1):95-102.

   OpenUrl
9. 9.↵
   1. Goldbart A,
   2. Golan-Tripto I,
   3. Pillar G,
   4. Livnat-Levanon G,
   5. Efrati O,
   6. Spiegel R,
   7. et al

   . Inhaled nitric oxide therapy in acute bronchiolitis: A multi-center randomized clinical trial. Sci Rep 2020;10(1):9605.

   OpenUrl
10. 10.↵
    1. Bartley BL,
    2. Gardner KJ,
    3. Spina S,
    4. Hurley BP,
    5. Campeau D,
    6. Berra L,
    7. et al

    . High-dose inhaled nitric oxide as adjunct therapy in cystic fibrosis targeting Burkholderia multivorans. Case Rep Pediatr 2020;2020:1536714.

    OpenUrl
11. 11.↵
    1. Akaberi D,
    2. Krambrich J,
    3. Ling J,
    4. Luni C,
    5. Hedenstierna G,
    6. Järhult JD,
    7. et al

    . Mitigation of the replication of SARS-CoV-2 by nitric oxide in Vitro. Redox Biol 2020;37:101734.

    OpenUrl
12. 12.↵
    1. Todd Tzanetos DR,
    2. Housley JJ,
    3. Barr FE,
    4. May WL,
    5. Landers CD

    . Implementation of an inhaled nitric oxide protocol decreases direct cost associated with its use. Respir Care 2015;60(5):644-650.

    OpenUrlAbstract/FREE Full Text
13. 13.↵
    1. Pierce CM,
    2. Peters MJ,
    3. Cohen G,
    4. Goldman AP,
    5. Petros AJ

    . Cost of nitric oxide is exorbitant. BMJ 2002;325(7359):336.

    OpenUrlFREE Full Text
14. 14.↵
    1. Namihira T,
    2. Katsuki S,
    3. Hackam R,
    4. Akiyama H,
    5. Okamoto K

    . Production of nitric oxide using a pulsed arc discharge. IEEE Trans Plasma Sci 2002;30(5):1993-1998.

    OpenUrl
15. 15.↵
    1. Namihira T,
    2. Tsukamoto S,
    3. Wang D,
    4. Katsuki S,
    5. Hackam R,
    6. Okamoto K,
    7. et al

    . Production of nitric monoxide using pulsed discharges for a medical application. IEEE Trans Plasma Sci 2000;28(1):109-114.

    OpenUrl
16. 16.↵
    1988 OSHA PEL Project - Nitrogen Dioxide | NIOSH | CDC [Internet]. 2020 [cited 2020 May 31]. Available at: https://www.cdc.gov/niosh/pel88/10102-44.html
17. 17.↵
    1. Yu B,
    2. Blaesi AH,
    3. Casey N,
    4. Raykhtsaum G,
    5. Zazzeron L,
    6. Jones R,
    7. et al

    . Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge. Nitric Oxide 2016;60:16-23.

    OpenUrl
18. 18.↵
    1. Gianni S,
    2. Morais CCA,
    3. Larson G,
    4. Pinciroli R,
    5. Carroll R,
    6. Yu B,
    7. et al

    . Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects. Nitric Oxide 2020;104-105:29-35.

    OpenUrl
19. 19.↵
    1. Yu B,
    2. Muenster S,
    3. Blaesi AH,
    4. Bloch DB,
    5. Zapol WM

    . Producing nitric oxide by pulsed electrical discharge in air for portable inhalation therapy. Sci Transl Med 2015;7(294):294ra107.

    OpenUrlAbstract/FREE Full Text
20. 20.↵
    1. Safaee Fakhr B,
    2. Wiegand SB,
    3. Pinciroli R,
    4. Gianni S,
    5. Morais CCA,
    6. Ikeda T,
    7. et al

    . High concentrations of nitric oxide inhalation therapy in pregnant patients with severe coronavirus disease 2019 (COVID-19). Obstet Gynecol 2020 Dec;136(6):1109-1113.

    OpenUrl